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Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 5' and Ligand = 'BDBM364175'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))		BDBM364175
PNG
(US9856252, 67)
Show SMILES OC(=O)c1cc(ccc1OCc1ccccc1)-c1nc2cc(cnc2[nH]1)C1CCNCC1
Show InChI InChI=1S/C25H24N4O3/c30-25(31)20-12-18(6-7-22(20)32-15-16-4-2-1-3-5-16)23-28-21-13-19(14-27-24(21)29-23)17-8-10-26-11-9-17/h1-7,12-14,17,26H,8-11,15H2,(H,30,31)(H,27,28,29)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 3.72E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Company



Assay Description
The 6 μL assay reactions are run in Greiner brand black 384-well low volume plates. All reactions contained assay buffer (phosphate buffered sal...

J Med Chem 49: 2440-55 (2006)


BindingDB Entry DOI: 10.7270/Q2BK1FNV
More data for this
Ligand-Target Pair