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Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 5' and Ligand = 'BDBM364180'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))		BDBM364180
PNG
(US9856252, 72)
Show SMILES CCS(=O)(=O)N1CCN(CC1)c1ccc2nc([nH]c2n1)-c1ccc(OCc2ccccc2)c(c1)-c1cncnc1
Show InChI InChI=1S/C29H29N7O3S/c1-2-40(37,38)36-14-12-35(13-15-36)27-11-9-25-29(33-27)34-28(32-25)22-8-10-26(39-19-21-6-4-3-5-7-21)24(16-22)23-17-30-20-31-18-23/h3-11,16-18,20H,2,12-15,19H2,1H3,(H,32,33,34)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 1.71E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company



Assay Description
The 6 μL assay reactions are run in Greiner brand black 384-well low volume plates. All reactions contained assay buffer (phosphate buffered sal...

J Med Chem 49: 2440-55 (2006)


BindingDB Entry DOI: 10.7270/Q2BK1FNV
More data for this
Ligand-Target Pair