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Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 5' and Ligand = 'BDBM364203'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))		BDBM364203
PNG
(US9856252, 95)
Show SMILES CC(C)(C)OC(=O)N1CCN(CC1)c1ccc2nc([nH]c2n1)-c1ccc(SCc2ccccc2)cc1
Show InChI InChI=1S/C28H31N5O2S/c1-28(2,3)35-27(34)33-17-15-32(16-18-33)24-14-13-23-26(30-24)31-25(29-23)21-9-11-22(12-10-21)36-19-20-7-5-4-6-8-20/h4-14H,15-19H2,1-3H3,(H,29,30,31)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 2.82E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Company



Assay Description
The 6 μL assay reactions are run in Greiner brand black 384-well low volume plates. All reactions contained assay buffer (phosphate buffered sal...

J Med Chem 49: 2440-55 (2006)


BindingDB Entry DOI: 10.7270/Q2BK1FNV
More data for this
Ligand-Target Pair