BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 5' and Ligand = 'BDBM451349'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))		BDBM451349
PNG
(US10709709, Example 179)
Show SMILES Cc1cn([C@@H]2C[C@H](Oc3cc(F)c(F)c4CCNCc34)[C@@H](O)[C@H]2O)c2nc(C)nc(N)c12 |r|
Show InChI InChI=1S/C22H25F2N5O3/c1-9-8-29(22-17(9)21(25)27-10(2)28-22)14-6-16(20(31)19(14)30)32-15-5-13(23)18(24)11-3-4-26-7-12(11)15/h5,8,14,16,19-20,26,30-31H,3-4,6-7H2,1-2H3,(H2,25,27,28)/t14-,16+,19+,20-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
Compounds were solubilized in DMSO and serially diluted, using 3-fold dilutions, into 100% DMSO at a concentration 50-fold greater than the desired a...

US Patent US10709709 (2020)


BindingDB Entry DOI: 10.7270/Q26113CC
More data for this
Ligand-Target Pair