Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein c-Fos/Transcription factor Jun' and Ligand = 'BDBM50090411'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090411 (2-(2,6-Dichloro-pyridin-4-yl)-4-(3-methyl-2,5-diox...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1cc(Cl)nc(Cl)c1 |t:16| Show InChI InChI=1S/C17H13Cl2N5O4/c1-3-28-17(27)10-7-20-14(9-5-11(18)21-12(19)6-9)22-15(10)23-24-13(25)4-8(2)16(24)26/h4-7H,3H2,1-2H3,(H,20,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
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