Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase alpha subunit/subunit beta' and Ligand = 'BDBM238353'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase alpha subunit/subunit beta (Trypanosoma brucei brucei)	BDBM238353 (3-(4-Chlorophenyl)-4-cyano-5-(isopropylthio)thioph...) Show SMILES CC(C)Sc1sc(C(O)=O)c(c1C#N)-c1ccc(Cl)cc1 Show InChI InChI=1S/C15H12ClNO2S2/c1-8(2)20-15-11(7-17)12(13(21-15)14(18)19)9-3-5-10(16)6-4-9/h3-6,8H,1-2H3,(H,18,19)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche de Gif					Assay Description Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...				J Enzyme Inhib Med Chem 28: 163-71 (2013) Article DOI: 10.3109/14756366.2011.643302 BindingDB Entry DOI: 10.7270/Q2319TSJ
					More data for this Ligand-Target Pair