Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50048959'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50048959 (4'-((R)-2-Amino-3-mercapto-propylamino)-biphenyl-4...) Show SMILES N[C@@H](CS)CNc1ccc(cc1)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C16H18N2O2S/c17-14(10-21)9-18-15-7-5-12(6-8-15)11-1-3-13(4-2-11)16(19)20/h1-8,14,18,21H,9-10,17H2,(H,19,20)/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description In vitro inhibition of Farnesyltransferase				J Med Chem 39: 217-23 (1996) Article DOI: 10.1021/jm950414g BindingDB Entry DOI: 10.7270/Q23J3DM7
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