Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50051832'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50051832 (CHEMBL440280 | [((2E,6E,10E)-3,7,11,15-Tetramethyl...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#8]-[#7]-[#6](=O)-[#6]P([#8])([#8])=O Show InChI InChI=1S/C22H38NO5P/c1-18(2)9-6-10-19(3)11-7-12-20(4)13-8-14-21(5)15-16-28-23-22(24)17-29(25,26)27/h9,11,13,15H,6-8,10,12,14,16-17H2,1-5H3,(H,23,24)(H2,25,26,27)/b19-11+,20-13+,21-15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl protein transferase				Bioorg Med Chem Lett 13: 4405-8 (2003) BindingDB Entry DOI: 10.7270/Q2NG4Q10
					More data for this Ligand-Target Pair