Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50060139'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50060139 (CHEMBL326352 | [(S)-1-((4-Benzyloxy-benzyl)-{[(1-p...) Show SMILES O=C(CN(Cc1ccc(OCc2ccccc2)cc1)C(=O)[C@H](Cc1cnc[nH]1)NC(=O)OCc1ccccc1)NCC1(CCC1)c1ccccc1 Show InChI InChI=1S/C41H43N5O5/c47-38(43-29-41(21-10-22-41)34-15-8-3-9-16-34)26-46(25-31-17-19-36(20-18-31)50-27-32-11-4-1-5-12-32)39(48)37(23-35-24-42-30-44-35)45-40(49)51-28-33-13-6-2-7-14-33/h1-9,11-20,24,30,37H,10,21-23,25-29H2,(H,42,44)(H,43,47)(H,45,49)/t37-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro inhibition of rat farnesyltransferase.				J Med Chem 40: 3319-22 (1997) Article DOI: 10.1021/jm970470c BindingDB Entry DOI: 10.7270/Q2V69HQG
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