Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50078816'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50078816 (1-[4-(3-Cyclopropyl-10-methoxy-8-methyl-6,11-dihyd...) Show SMILES COc1cc(C)cc2CCc3cc(cnc3C(C3CCN(CC3)C(=O)Cc3cc[n+]([O-])cc3)c12)C1CC1 Show InChI InChI=1S/C31H35N3O3/c1-20-15-24-5-6-25-18-26(22-3-4-22)19-32-31(25)30(29(24)27(16-20)37-2)23-9-11-33(12-10-23)28(35)17-21-7-13-34(36)14-8-21/h7-8,13-16,18-19,22-23,30H,3-6,9-12,17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of human Farnesyltransferase				Bioorg Med Chem Lett 9: 1875-80 (1999) BindingDB Entry DOI: 10.7270/Q29W0DQR
					More data for this Ligand-Target Pair