Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50079671'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50079671 ((S)-2-(3-{[Bis-(1H-imidazol-4-ylmethyl)-amino]-met...) Show SMILES CSCC[C@H](NC(=O)c1cccc(CN(Cc2cnc[nH]2)Cc2cnc[nH]2)c1)C(O)=O Show InChI InChI=1S/C21H26N6O3S/c1-31-6-5-19(21(29)30)26-20(28)16-4-2-3-15(7-16)10-27(11-17-8-22-13-24-17)12-18-9-23-14-25-18/h2-4,7-9,13-14,19H,5-6,10-12H2,1H3,(H,22,24)(H,23,25)(H,26,28)(H,29,30)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into recombinant Ha-Ras by bovine brain farensyltransferase				Bioorg Med Chem Lett 9: 1991-6 (1999) BindingDB Entry DOI: 10.7270/Q2ZG6RFB
					More data for this Ligand-Target Pair