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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50079807'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Mus musculus)		BDBM50079807
PNG
(CHEMBL294277 | methyl 2-[1-[4-amino-5-sulfanyl-(E,...)
Show SMILES COC(=O)[C@H](CCSC)NC(=O)[C@@H]1C[C@@H](CN1C\C=C\[C@@H](N)CS)Oc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C23H32F3N3O4S2/c1-32-22(31)19(9-11-35-2)28-21(30)20-12-18(13-29(20)10-3-4-16(27)14-34)33-17-7-5-15(6-8-17)23(24,25)26/h3-8,16,18-20,34H,9-14,27H2,1-2H3,(H,28,30)/b4-3+/t16-,18+,19+,20+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Eisai Research Institute

Curated by ChEMBL


Assay Description
Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-ras

Bioorg Med Chem Lett 9: 2095-100 (1999)


BindingDB Entry DOI: 10.7270/Q2Z038PQ
More data for this
Ligand-Target Pair