Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50084823'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50084823 (2,4,7-Trinitro-5-(piperidine-1-carbonyl)-fluoren-9...) Show SMILES [O-][N+](=O)c1cc2C(=O)c3cc(cc(c3-c2c(c1)C(=O)N1CCCCC1)[N+]([O-])=O)[N+]([O-])=O Show InChI InChI=1S/C19H14N4O8/c24-18-12-6-10(21(26)27)8-14(19(25)20-4-2-1-3-5-20)16(12)17-13(18)7-11(22(28)29)9-15(17)23(30)31/h6-9H,1-5H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Medical School and Mayo Clinic Curated by ChEMBL					Assay Description In vitro inhibition of Farnesyltransferase (FT) by using FT [3H]-SPA kit.				J Med Chem 43: 401-8 (2000) BindingDB Entry DOI: 10.7270/Q28W3F0K
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