Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50098010'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50098010 (CHEMBL433529 | N-Isopropyl-2-(2-phenyl-1H-indol-3-...) Show SMILES CC(C)N(Cc1cncnc1)C(=O)Cc1c([nH]c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C24H24N4O/c1-17(2)28(15-18-13-25-16-26-14-18)23(29)12-21-20-10-6-7-11-22(20)27-24(21)19-8-4-3-5-9-19/h3-11,13-14,16-17,27H,12,15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	232	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Concentration required for the inhibitory activity against human Farnesyltransferase				Bioorg Med Chem Lett 11: 865-9 (2001) BindingDB Entry DOI: 10.7270/Q2F47PPX
					More data for this Ligand-Target Pair