Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50098029'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50098029 (2-(2-Phenyl-1H-indol-3-yl)-N,N-bis-pyridin-3-ylmet...) Show SMILES O=C(Cc1c([nH]c2ccccc12)-c1ccccc1)N(Cc1cccnc1)Cc1cccnc1 Show InChI InChI=1S/C28H24N4O/c33-27(32(19-21-8-6-14-29-17-21)20-22-9-7-15-30-18-22)16-25-24-12-4-5-13-26(24)31-28(25)23-10-2-1-3-11-23/h1-15,17-18,31H,16,19-20H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Concentration required for the inhibitory activity against human Farnesyltransferase				Bioorg Med Chem Lett 11: 865-9 (2001) BindingDB Entry DOI: 10.7270/Q2F47PPX
					More data for this Ligand-Target Pair