Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50098042'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50098042 (CHEMBL354580 | N-Isobutyl-2-(2-phenyl-1H-indol-3-y...) Show SMILES CC(C)CN(Cc1cccnc1)C(=O)Cc1c([nH]c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C26H27N3O/c1-19(2)17-29(18-20-9-8-14-27-16-20)25(30)15-23-22-12-6-7-13-24(22)28-26(23)21-10-4-3-5-11-21/h3-14,16,19,28H,15,17-18H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Concentration required for the inhibitory activity against human Farnesyltransferase				Bioorg Med Chem Lett 11: 865-9 (2001) BindingDB Entry DOI: 10.7270/Q2F47PPX
					More data for this Ligand-Target Pair