Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50103257'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Saccharomyces cerevisiae (Baker's yeast))	BDBM50103257 (1-[3-Benzoyl-4-(4-carboxy-butyrylamino)-phenylcarb...) Show SMILES [NH3+][C@@H](CS)C(=O)Nc1ccc(NC(=O)CCCC(O)=O)c(c1)C(=O)c1ccccc1 Show InChI InChI=1S/C21H23N3O5S/c22-16(12-30)21(29)23-14-9-10-17(24-18(25)7-4-8-19(26)27)15(11-14)20(28)13-5-2-1-3-6-13/h1-3,5-6,9-11,16,30H,4,7-8,12,22H2,(H,23,29)(H,24,25)(H,26,27)/p+1/t16-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Philipps-Universität Marburg Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase.				J Med Chem 44: 2886-99 (2001) BindingDB Entry DOI: 10.7270/Q2TQ60TB
					More data for this Ligand-Target Pair