Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50106863'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50106863 (CHEMBL432008 | [1-(3H-Imidazol-4-ylmethyl)-4-napht...) Show SMILES O=C(N1CCOCC1)c1cn(Cc2cnc[nH]2)cc1-c1cccc2ccccc12 Show InChI InChI=1S/C23H22N4O2/c28-23(27-8-10-29-11-9-27)22-15-26(13-18-12-24-16-25-18)14-21(22)20-7-3-5-17-4-1-2-6-19(17)20/h1-7,12,14-16H,8-11,13H2,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
LGCI Curated by ChEMBL					Assay Description Inhibition of farnesyltransferase activity against H-Ras				Bioorg Med Chem Lett 11: 3069-72 (2001) BindingDB Entry DOI: 10.7270/Q2ZW1K7T
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50106863 (CHEMBL432008 | [1-(3H-Imidazol-4-ylmethyl)-4-napht...) Show SMILES O=C(N1CCOCC1)c1cn(Cc2cnc[nH]2)cc1-c1cccc2ccccc12 Show InChI InChI=1S/C23H22N4O2/c28-23(27-8-10-29-11-9-27)22-15-26(13-18-12-24-16-25-18)14-21(22)20-7-3-5-17-4-1-2-6-19(17)20/h1-7,12,14-16H,8-11,13H2,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
LGCI Curated by ChEMBL					Assay Description Inhibition of farnesyltransferase activity against K-Ras				Bioorg Med Chem Lett 11: 3069-72 (2001) BindingDB Entry DOI: 10.7270/Q2ZW1K7T
					More data for this Ligand-Target Pair