Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50106867'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50106867 (CHEMBL318072 | [1-(3H-Imidazol-4-ylmethyl)-4-pheny...) Show SMILES O=C(N1CCOCC1)c1cn(Cc2cnc[nH]2)cc1-c1ccccc1 Show InChI InChI=1S/C19H20N4O2/c24-19(23-6-8-25-9-7-23)18-13-22(11-16-10-20-14-21-16)12-17(18)15-4-2-1-3-5-15/h1-5,10,12-14H,6-9,11H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
LGCI Curated by ChEMBL					Assay Description Inhibition of farnesyltransferase activity against H-Ras				Bioorg Med Chem Lett 11: 3069-72 (2001) BindingDB Entry DOI: 10.7270/Q2ZW1K7T
					More data for this Ligand-Target Pair