Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50114324'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50114324 (4-Methyl-benzoic acid (S)-2-[(S)-2-((R)-2-amino-3-...) Show SMILES COC(=O)[C@H](COC(=O)c1ccc(C)cc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C Show InChI InChI=1S/C20H29N3O6S/c1-11(2)16(23-17(24)14(21)10-30)18(25)22-15(20(27)28-4)9-29-19(26)13-7-5-12(3)6-8-13/h5-8,11,14-16,30H,9-10,21H2,1-4H3,(H,22,25)(H,23,24)/t14-,15-,16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry and School of Molecular Science(BK21) Curated by ChEMBL					Assay Description In vitro inhibition of bovine Farnesyltrasferase.				Bioorg Med Chem Lett 12: 1599-602 (2002) BindingDB Entry DOI: 10.7270/Q24B30MH
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