Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50127318'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50127318 (5-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(3-methyl-...) Show SMILES Cn1cncc1C(OCc1nc(N2CCOCC2)c(cc1-c1cccc(Cl)c1)C#N)c1ccc(cc1)C#N Show InChI InChI=1S/C29H25ClN6O2/c1-35-19-33-17-27(35)28(21-7-5-20(15-31)6-8-21)38-18-26-25(22-3-2-4-24(30)13-22)14-23(16-32)29(34-26)36-9-11-37-12-10-36/h2-8,13-14,17,19,28H,9-12,18H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of transfer of [3H]-FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTase				Bioorg Med Chem Lett 13: 1571-4 (2003) BindingDB Entry DOI: 10.7270/Q27080TK
					More data for this Ligand-Target Pair