Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50127322'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50127322 (5-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...) Show SMILES Cn1cncc1C(OCc1ccc(nc1-c1cc(F)cc(F)c1)C#N)c1ccc(cc1)C#N Show InChI InChI=1S/C25H17F2N5O/c1-32-15-30-13-23(32)25(17-4-2-16(11-28)3-5-17)33-14-18-6-7-22(12-29)31-24(18)19-8-20(26)10-21(27)9-19/h2-10,13,15,25H,14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of transfer of [3H]-FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTase				Bioorg Med Chem Lett 13: 1571-4 (2003) BindingDB Entry DOI: 10.7270/Q27080TK
					More data for this Ligand-Target Pair