Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50127331'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50127331 (6-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...) Show SMILES CN1CCN(CC1)c1nc(COC(c2cncn2C)c2ccc(cc2)C#N)ccc1C#N Show InChI InChI=1S/C24H25N7O/c1-29-9-11-31(12-10-29)24-20(14-26)7-8-21(28-24)16-32-23(22-15-27-17-30(22)2)19-5-3-18(13-25)4-6-19/h3-8,15,17,23H,9-12,16H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP transfer to biotin K-ras peptide (KKSKTKCVIM) by bovine FTase				Bioorg Med Chem Lett 13: 1571-4 (2003) BindingDB Entry DOI: 10.7270/Q27080TK
					More data for this Ligand-Target Pair