Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50134562'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50134562 (4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...) Show SMILES Cn1cncc1C(OCc1ccc(cc1C#CCCc1ccccc1)C#N)c1ccc(cc1)C#N Show InChI InChI=1S/C30H24N4O/c1-34-22-33-20-29(34)30(26-14-11-24(18-31)12-15-26)35-21-28-16-13-25(19-32)17-27(28)10-6-5-9-23-7-3-2-4-8-23/h2-4,7-8,11-17,20,22,30H,5,9,21H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of the human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIM.				Bioorg Med Chem Lett 13: 3821-5 (2003) BindingDB Entry DOI: 10.7270/Q2319V9P
					More data for this Ligand-Target Pair