Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50135376'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50135376 (5-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(2,3-dimet...) Show SMILES Cc1ncc(C(OCc2c(cc(C#N)c(=O)n2C)-c2cccc(Cl)c2)c2ccc(cc2)C#N)n1C Show InChI InChI=1S/C27H22ClN5O2/c1-17-31-15-24(32(17)2)26(19-9-7-18(13-29)8-10-19)35-16-25-23(20-5-4-6-22(28)11-20)12-21(14-30)27(34)33(25)3/h4-12,15,26H,16H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against farnesyltransferase (FT)				Bioorg Med Chem Lett 13: 4001-5 (2003) BindingDB Entry DOI: 10.7270/Q2H41QVX
					More data for this Ligand-Target Pair