Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50135393'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50135393 (5-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(3H-imidaz...) Show SMILES Cn1c(COC(c2cnc[nH]2)c2ccc(cc2)C#N)c(cc(C#N)c1=O)-c1cccc(Cl)c1 Show InChI InChI=1S/C25H18ClN5O2/c1-31-23(21(10-19(12-28)25(31)32)18-3-2-4-20(26)9-18)14-33-24(22-13-29-15-30-22)17-7-5-16(11-27)6-8-17/h2-10,13,15,24H,14H2,1H3,(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against farnesyltransferase (FT)				Bioorg Med Chem Lett 13: 4001-5 (2003) BindingDB Entry DOI: 10.7270/Q2H41QVX
					More data for this Ligand-Target Pair