Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50150666'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150666 ((S)-2-({(2S,3S,6R)-6-[((R)-2-Amino-3-tert-butyldis...) Show SMILES CS(=O)CC[C@H](NC(=O)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C26H41N3O7S3/c1-26(2,3)38-37-16-19(27)23(30)28-14-18-10-11-21(35-15-17-8-6-5-7-9-17)22(36-18)24(31)29-20(25(32)33)12-13-39(4)34/h5-9,18-22H,10-16,27H2,1-4H3,(H,28,30)(H,29,31)(H,32,33)/t18-,19+,20+,21+,22+,39?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation by Protein Farnesyltransferase				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair