Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50153779'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50153779 (4-((5-(((3',5-dichlorobiphenyl-2-yl)methoxy)methyl...) Show SMILES Clc1cccc(c1)-c1cc(Cl)ccc1COCc1cncn1Cc1ccc(cc1)C#N Show InChI InChI=1S/C25H19Cl2N3O/c26-22-3-1-2-20(10-22)25-11-23(27)9-8-21(25)15-31-16-24-13-29-17-30(24)14-19-6-4-18(12-28)5-7-19/h1-11,13,17H,14-16H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.620	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine farnesyltransferase				Bioorg Med Chem Lett 14: 5371-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.011 BindingDB Entry DOI: 10.7270/Q2J102N8
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