Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50164006'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50164006 (CHEMBL361976 | N-[6-Cyano-1-(3-methyl-3H-imidazol-...) Show SMILES Cn1cncc1CN1CC(Cc2cc(ccc12)C#N)N(CCc1ccccc1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C29H29N5O2S/c1-32-22-31-19-27(32)21-33-20-26(17-25-16-24(18-30)12-13-29(25)33)34(15-14-23-8-4-2-5-9-23)37(35,36)28-10-6-3-7-11-28/h2-13,16,19,22,26H,14-15,17,20-21H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human farnesyltransferase				Bioorg Med Chem Lett 15: 1895-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.004 BindingDB Entry DOI: 10.7270/Q2RB75CJ
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