Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50283540'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50283540 ((S)-2-{3-[((R)-2-Amino-3-mercapto-propionylamino)-...) Show SMILES CSCC[C@H](NC(=O)c1cccc(CNC(=O)[C@@H]([NH3+])CS)c1)C([O-])=O Show InChI InChI=1S/C16H23N3O4S2/c1-25-6-5-13(16(22)23)19-14(20)11-4-2-3-10(7-11)8-18-15(21)12(17)9-24/h2-4,7,12-13,24H,5-6,8-9,17H2,1H3,(H,18,21)(H,19,20)(H,22,23)/t12-,13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase				Bioorg Med Chem Lett 4: 2775-2780 (1994) Article DOI: 10.1016/S0960-894X(01)80593-X BindingDB Entry DOI: 10.7270/Q21J99Q0
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50283540 ((S)-2-{3-[((R)-2-Amino-3-mercapto-propionylamino)-...) Show SMILES CSCC[C@H](NC(=O)c1cccc(CNC(=O)[C@@H]([NH3+])CS)c1)C([O-])=O Show InChI InChI=1S/C16H23N3O4S2/c1-25-6-5-13(16(22)23)19-14(20)11-4-2-3-10(7-11)8-18-15(21)12(17)9-24/h2-4,7,12-13,24H,5-6,8-9,17H2,1H3,(H,18,21)(H,19,20)(H,22,23)/t12-,13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]FPP incorporation into recombinant P21ras of NIH3T3 cells by farnesyl transferase				Bioorg Med Chem Lett 4: 2579-2584 (1994) Article DOI: 10.1016/S0960-894X(01)80287-0 BindingDB Entry DOI: 10.7270/Q29C6XXR
					More data for this Ligand-Target Pair