Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50288500'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50288500 (11-[1-(Butane-1-sulfonyl)-piperidin-4-ylidene]-8-c...) Show SMILES [#6]-[#6]-[#6]-[#6]S(=O)(=O)[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2cccnc-12 Show InChI InChI=1S/C23H27ClN2O2S/c1-2-3-15-29(27,28)26-13-10-17(11-14-26)22-21-9-8-20(24)16-19(21)7-6-18-5-4-12-25-23(18)22/h4-5,8-9,12,16H,2-3,6-7,10-11,13-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against protein farnesyltransferase.				Bioorg Med Chem Lett 6: 2977-2982 (1996) Article DOI: 10.1016/S0960-894X(96)00558-6 BindingDB Entry DOI: 10.7270/Q2B56JQR
					More data for this Ligand-Target Pair