Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50288509'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50288509 ((S)-2-Amino-1-[4-(8-chloro-5,6-dihydro-benzo[5,6]c...) Show SMILES [#6]-[#8]-c1ccc(-[#6]-[#16]-[#6]-[#6@@H](-[#7])-[#6](=O)-[#7]-2-[#6]-[#6]\[#6](-[#6]-[#6]-2)=[#6]-2\c3ccc(Cl)cc3-[#6]-[#6]-c3cccnc-23)cc1 Show InChI InChI=1S/C30H32ClN3O2S/c1-36-25-9-4-20(5-10-25)18-37-19-27(32)30(35)34-15-12-21(13-16-34)28-26-11-8-24(31)17-23(26)7-6-22-3-2-14-33-29(22)28/h2-5,8-11,14,17,27H,6-7,12-13,15-16,18-19,32H2,1H3/t27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	6.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against protein farnesyltransferase.				Bioorg Med Chem Lett 6: 2977-2982 (1996) Article DOI: 10.1016/S0960-894X(96)00558-6 BindingDB Entry DOI: 10.7270/Q2B56JQR
					More data for this Ligand-Target Pair