Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50289421'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50289421 (3-[4-((R)-2-Amino-3-mercapto-propionylamino)-pheno...) Show SMILES N[C@@H](CS)C(=O)Nc1ccc(Oc2cccc(c2)C(O)=O)cc1 Show InChI InChI=1S/C16H16N2O4S/c17-14(9-23)15(19)18-11-4-6-12(7-5-11)22-13-3-1-2-10(8-13)16(20)21/h1-8,14,23H,9,17H2,(H,18,19)(H,20,21)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 ...				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
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