Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50369365'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50369365 (CHEMBL1790754) Show SMILES CC[C@@H](C)[C@@H](CN(C)CC(=O)N[C@@H](CCO)C(O)=O)NC[C@@H](N)CS Show InChI InChI=1S/C16H34N4O4S/c1-4-11(2)14(18-7-12(17)10-25)8-20(3)9-15(22)19-13(5-6-21)16(23)24/h11-14,18,21,25H,4-10,17H2,1-3H3,(H,19,22)(H,23,24)/t11-,12-,13+,14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine brain Farnesyltransferase at 10 pM				J Med Chem 41: 2651-6 (1998) Article DOI: 10.1021/jm9800907 BindingDB Entry DOI: 10.7270/Q2WW7JCV
					More data for this Ligand-Target Pair