Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50369367'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50369367 (CHEMBL1790757) Show SMILES CC[C@@H](C)[C@@H](CN[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(O)=O)NC[C@@H](N)CS Show InChI InChI=1S/C20H42N4O3S2/c1-6-13(3)17(22-10-15(21)12-28)11-23-18(14(4)7-2)19(25)24-16(20(26)27)8-9-29-5/h13-18,22-23,28H,6-12,21H2,1-5H3,(H,24,25)(H,26,27)/t13-,14+,15-,16+,17-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation into recombinant human Ha-Ras by Farnesyltransferase				J Med Chem 41: 2651-6 (1998) Article DOI: 10.1021/jm9800907 BindingDB Entry DOI: 10.7270/Q2WW7JCV
					More data for this Ligand-Target Pair