Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50369368'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50369368 (CHEMBL1790744) Show SMILES CCC[C@H](N(C)C[C@@H](NC[C@@H](N)CS)[C@H](C)CC)C(=O)N[C@@H](CCO)C(O)=O Show InChI InChI=1S/C19H40N4O4S/c1-5-7-17(18(25)22-15(8-9-24)19(26)27)23(4)11-16(13(3)6-2)21-10-14(20)12-28/h13-17,21,24,28H,5-12,20H2,1-4H3,(H,22,25)(H,26,27)/t13-,14-,15+,16-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation into recombinant human Ha-Ras by Farnesyltransferase				J Med Chem 41: 2651-6 (1998) Article DOI: 10.1021/jm9800907 BindingDB Entry DOI: 10.7270/Q2WW7JCV
					More data for this Ligand-Target Pair