Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50481629'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50481629 (CHEMBL586003) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6](=O)-[#6]-[#6]-[#6]-[#6](-[#8])=O Show InChI InChI=1S/C20H32O3/c1-16(2)8-5-9-17(3)10-6-11-18(4)14-15-19(21)12-7-13-20(22)23/h8,10,14H,5-7,9,11-13,15H2,1-4H3,(H,22,23)/b17-10+,18-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche de Gif-sur-Yvette Curated by ChEMBL					Assay Description Inhibition of human recombinant FTase by fluorescent-based assay				Bioorg Med Chem 18: 543-56 (2010) Article DOI: 10.1016/j.bmc.2009.12.017 BindingDB Entry DOI: 10.7270/Q2VM4G37
					More data for this Ligand-Target Pair