Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50483439'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50483439 (CHEMBL1683674) Show SMILES C[C@@H]1CCC(=O)[C@H](C)[C@@]1(C)CCC(=C)C(O)Cc1c(O)cc(C)cc1O |r| Show InChI InChI=1S/C22H32O4/c1-13-10-20(25)17(21(26)11-13)12-19(24)14(2)8-9-22(5)15(3)6-7-18(23)16(22)4/h10-11,15-16,19,24-26H,2,6-9,12H2,1,3-5H3/t15-,16+,19?,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Keio University Curated by ChEMBL					Assay Description Inhibition of protein farnesyltransferase from human EC17 cells using [3H]FPP and GTP-H-Ras				Bioorg Med Chem Lett 21: 1385-9 (2011) Article DOI: 10.1016/j.bmcl.2011.01.028 BindingDB Entry DOI: 10.7270/Q2SX6H2F
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