Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50483442'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50483442 (CHEMBL1683668) Show SMILES Cc1cccc(C)c1CCC(=C)C(O)Cc1c(O)cc(C)c(C=O)c1O Show InChI InChI=1S/C22H26O4/c1-13-6-5-7-14(2)17(13)9-8-15(3)20(24)11-18-21(25)10-16(4)19(12-23)22(18)26/h5-7,10,12,20,24-26H,3,8-9,11H2,1-2,4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Keio University Curated by ChEMBL					Assay Description Inhibition of protein farnesyltransferase from human EC17 cells using [3H]FPP and GTP-H-Ras				Bioorg Med Chem Lett 21: 1385-9 (2011) Article DOI: 10.1016/j.bmcl.2011.01.028 BindingDB Entry DOI: 10.7270/Q2SX6H2F
					More data for this Ligand-Target Pair