Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50497172'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50497172 (CHEMBL3286836) Show SMILES CSCC[C@H](NC(=O)c1ccc(OCC2COc3ccccc3O2)cc1-c1ccsc1)C(O)=O |r| Show InChI InChI=1S/C25H25NO6S2/c1-33-10-9-21(25(28)29)26-24(27)19-7-6-17(12-20(19)16-8-11-34-15-16)30-13-18-14-31-22-4-2-3-5-23(22)32-18/h2-8,11-12,15,18,21H,9-10,13-14H2,1H3,(H,26,27)(H,28,29)/t18?,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Milano Curated by ChEMBL					Assay Description Inhibition of recombinant FTase (unknown origin) by spectrofluorimetric analysis				Bioorg Med Chem Lett 24: 2924-7 (2014) Article DOI: 10.1016/j.bmcl.2014.04.078 BindingDB Entry DOI: 10.7270/Q2K35XM2
					More data for this Ligand-Target Pair