Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein kinase C alpha type' and Ligand = 'BDBM251504'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C alpha type (Homo sapiens (Human))	BDBM251504 (US9452998, 53) Show SMILES NC1CCN(CC1)c1cccnc1NC(=O)c1nc(cnc1N)-c1nc(ccc1C(F)(F)F)N1CCC1 Show InChI InChI=1S/C24H26F3N9O/c25-24(26,27)15-4-5-18(36-9-2-10-36)33-19(15)16-13-31-21(29)20(32-16)23(37)34-22-17(3-1-8-30-22)35-11-6-14(28)7-12-35/h1,3-5,8,13-14H,2,6-7,9-12,28H2,(H2,29,31)(H,30,34,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	7.4	n/a
NOVARTIS AG US Patent					Assay Description The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...				US Patent US9452998 (2016) BindingDB Entry DOI: 10.7270/Q2C82870
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