Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein kinase C theta type (Homo sapiens (Human)) | BDBM35165 (3-pyridinecarbonitrile, 48) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl... | Bioorg Med Chem 17: 7933-48 (2009) Article DOI: 10.1016/j.bmc.2009.10.020 BindingDB Entry DOI: 10.7270/Q2M043RT | |||||||||||
More data for this Ligand-Target Pair |