Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Protein tyrosine phosphatase type IVA 3' and Ligand = 'BDBM396097'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein tyrosine phosphatase type IVA 3 (Homo sapiens (Human))	BDBM396097 (US10308663, JMS-631-053) Show SMILES N=C1c2sc(cc2C(=O)NC1=O)-c1ccccc1 Show InChI InChI=1S/C13H8N2O2S/c14-10-11-8(12(16)15-13(10)17)6-9(18-11)7-4-2-1-3-5-7/h1-6,14H,(H,15,16,17)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The in vitro biochemical evaluation of all compounds was carried out using recombinant human PTP4A3, overexpressed as a His6-tag fusion protein in E....				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q20867N2
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Protein tyrosine phosphatase type IVA 3 (Homo sapiens (Human))	BDBM396097 (US10308663, JMS-631-053) Show SMILES N=C1c2sc(cc2C(=O)NC1=O)-c1ccccc1 Show InChI InChI=1S/C13H8N2O2S/c14-10-11-8(12(16)15-13(10)17)6-9(18-11)7-4-2-1-3-5-7/h1-6,14H,(H,15,16,17)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human His6-tagged PRL-3 expressed in Escherichia coli using DiFMUP as substrate incubated for 30 mins by fluorescence based...				Citation and Details Article DOI: 10.1016/j.bmcl.2021.127981 BindingDB Entry DOI: 10.7270/Q2NK3JSF
					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 3 (Homo sapiens (Human))	BDBM396097 (US10308663, JMS-631-053) Show SMILES N=C1c2sc(cc2C(=O)NC1=O)-c1ccccc1 Show InChI InChI=1S/C13H8N2O2S/c14-10-11-8(12(16)15-13(10)17)6-9(18-11)7-4-2-1-3-5-7/h1-6,14H,(H,15,16,17)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant human His-6-tagged PTP4A3 expressed in Escherichia coli assessed as reduction in hydrolysis using DIFMUP as substrate incub...				Bioorg Med Chem Lett 29: 2008-2015 (2019) Article DOI: 10.1016/j.bmcl.2019.06.048 BindingDB Entry DOI: 10.7270/Q2VH5SBF
					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 3 (Homo sapiens (Human))	BDBM396097 (US10308663, JMS-631-053) Show SMILES N=C1c2sc(cc2C(=O)NC1=O)-c1ccccc1 Show InChI InChI=1S/C13H8N2O2S/c14-10-11-8(12(16)15-13(10)17)6-9(18-11)7-4-2-1-3-5-7/h1-6,14H,(H,15,16,17)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human PTP4A3				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128167 BindingDB Entry DOI: 10.7270/Q23X8BDD
					More data for this Ligand-Target Pair