Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein-serine O-palmitoleoyltransferase porcupine' and Ligand = 'BDBM50125942'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-serine O-palmitoleoyltransferase porcupine (Homo sapiens (Human))	BDBM50125942 (CHEMBL3623874) Show SMILES Cc1cc(ccn1)-c1ccc(OC(=O)Nc2ccc(cc2)-c2cccnc2)cc1 Show InChI InChI=1S/C24H19N3O2/c1-17-15-20(12-14-26-17)18-6-10-23(11-7-18)29-24(28)27-22-8-4-19(5-9-22)21-3-2-13-25-16-21/h2-16H,1H3,(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of porcupine (unknown origin) expressed in mouse L Wnt3A cells co-cultured with TM3 cells harboring luciferase reporter gene assessed as r...				Bioorg Med Chem 23: 6855-68 (2015) Article DOI: 10.1016/j.bmc.2015.09.048 BindingDB Entry DOI: 10.7270/Q2J10500
					More data for this Ligand-Target Pair