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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proteinase-activated receptor 1' and Ligand = 'BDBM50079758'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proteinase-activated receptor 1


(Homo sapiens (Human))		BDBM50079758
PNG
(7-(6-Methyl-naphthalen-2-ylmethyl)-7H-pyrrolo[3,2-...)
Show SMILES Cc1ccc2cc(Cn3ccc4c3ccc3nc(N)nc(N)c43)ccc2c1
Show InChI InChI=1S/C22H19N5/c1-13-2-4-16-11-14(3-5-15(16)10-13)12-27-9-8-17-19(27)7-6-18-20(17)21(23)26-22(24)25-18/h2-11H,12H2,1H3,(H4,23,24,25,26)
PDB

KEGG

UniProtKB/SwissProt

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DrugBank
antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.75E+3n/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)

Bioorg Med Chem Lett 9: 2073-8 (1999)


BindingDB Entry DOI: 10.7270/Q25X284B
More data for this
Ligand-Target Pair