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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50098211 ((S)-2-[(S)-2-{3-[1-(2,6-Dichloro-benzyl)-3-pyrroli...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM) | Bioorg Med Chem Lett 11: 2105-9 (2001) BindingDB Entry DOI: 10.7270/Q27W6BGF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50098211 ((S)-2-[(S)-2-{3-[1-(2,6-Dichloro-benzyl)-3-pyrroli...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM) | Bioorg Med Chem Lett 11: 2105-9 (2001) BindingDB Entry DOI: 10.7270/Q27W6BGF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50098211 ((S)-2-[(S)-2-{3-[1-(2,6-Dichloro-benzyl)-3-pyrroli...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro displacement of [3H]-S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 microM) from thrombin receptor (PAR-1) on the membranes of C... | Bioorg Med Chem Lett 11: 2105-9 (2001) BindingDB Entry DOI: 10.7270/Q27W6BGF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50098211 ((S)-2-[(S)-2-{3-[1-(2,6-Dichloro-benzyl)-3-pyrroli...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against Protease-activated receptor (PAR-1) using [3H]-s-(p-F-Phe)-homoarginine-L-homoarginine-KY-NH2, 10 nM (Kd= 15 nM) | J Med Chem 44: 1021-4 (2001) BindingDB Entry DOI: 10.7270/Q24X571D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
