Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50443584 (CHEMBL3091980) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Technology Curated by ChEMBL | Assay Description Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysis | ACS Med Chem Lett 4: 1054-8 (2013) Article DOI: 10.1021/ml400235c BindingDB Entry DOI: 10.7270/Q2KH0PSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50443584 (CHEMBL3091980) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Technology Curated by ChEMBL | Assay Description Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by... | ACS Med Chem Lett 4: 1054-8 (2013) Article DOI: 10.1021/ml400235c BindingDB Entry DOI: 10.7270/Q2KH0PSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50443584 (CHEMBL3091980) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 97 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Technology Curated by ChEMBL | Assay Description Antagonist activity at PAR1 in human platelet rich plasma assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followe... | ACS Med Chem Lett 4: 1054-8 (2013) Article DOI: 10.1021/ml400235c BindingDB Entry DOI: 10.7270/Q2KH0PSN | |||||||||||
More data for this Ligand-Target Pair |