Compile Data Set for Download or QSAR

Found 8 hits Enz. Inhib. hit(s) with Target = 'Proteinase-activated receptor 2' and Ligand = 'BDBM429569'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429569 (US10550089, Example 43 | US10550089, Example 44 | ...) Show SMILES OC(c1ncc[nH]1)c1ccc(F)c2occ(C3CC3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429569 (US10550089, Example 43 | US10550089, Example 44 | ...) Show SMILES OC(c1ncc[nH]1)c1ccc(F)c2occ(C3CC3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429569 (US10550089, Example 43 | US10550089, Example 44 | ...) Show SMILES OC(c1ncc[nH]1)c1ccc(F)c2occ(C3CC3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10995072 (2021) BindingDB Entry DOI: 10.7270/Q2D79FJQ
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429569 (US10550089, Example 43 | US10550089, Example 44 | ...) Show SMILES OC(c1ncc[nH]1)c1ccc(F)c2occ(C3CC3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429569 (US10550089, Example 43 | US10550089, Example 44 | ...) Show SMILES OC(c1ncc[nH]1)c1ccc(F)c2occ(C3CC3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...				US Patent US10995072 (2021) BindingDB Entry DOI: 10.7270/Q2D79FJQ
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429569 (US10550089, Example 43 | US10550089, Example 44 | ...) Show SMILES OC(c1ncc[nH]1)c1ccc(F)c2occ(C3CC3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429569 (US10550089, Example 43 | US10550089, Example 44 | ...) Show SMILES OC(c1ncc[nH]1)c1ccc(F)c2occ(C3CC3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429569 (US10550089, Example 43 | US10550089, Example 44 | ...) Show SMILES OC(c1ncc[nH]1)c1ccc(F)c2occ(C3CC3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair