Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Proteinase-activated receptor 2' and Ligand = 'BDBM50091326'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM50091326 (CHEMBL3582248) Show SMILES CC(C)c1cc(nn2cc(nc12)C(=O)N1CCN(CC1(C)C)C(=O)OC(C)(C)C)-c1ccc(F)cc1 Show InChI InChI=1S/C27H34FN5O3/c1-17(2)20-14-21(18-8-10-19(28)11-9-18)30-33-15-22(29-23(20)33)24(34)32-13-12-31(16-27(32,6)7)25(35)36-26(3,4)5/h8-11,14-15,17H,12-13,16H2,1-7H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Antagonist activity against PAR2 in human HT29 cells assessed as inhibition of SLIGKV-induced Ca2+ responses pre-incubated for 30 mins before SLIGKV ...				ACS Med Chem Lett 6: 487-8 (2015) Article DOI: 10.1021/acsmedchemlett.5b00147 BindingDB Entry DOI: 10.7270/Q27W6DX3
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM50091326 (CHEMBL3582248) Show SMILES CC(C)c1cc(nn2cc(nc12)C(=O)N1CCN(CC1(C)C)C(=O)OC(C)(C)C)-c1ccc(F)cc1 Show InChI InChI=1S/C27H34FN5O3/c1-17(2)20-14-21(18-8-10-19(28)11-9-18)30-33-15-22(29-23(20)33)24(34)32-13-12-31(16-27(32,6)7)25(35)36-26(3,4)5/h8-11,14-15,17H,12-13,16H2,1-7H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Antagonist activity against PAR2 in human HT29 cells assessed as inhibition of trypsin-induced Ca2+ responses pre-incubated for 30 mins before trypsi...				ACS Med Chem Lett 6: 487-8 (2015) Article DOI: 10.1021/acsmedchemlett.5b00147 BindingDB Entry DOI: 10.7270/Q27W6DX3
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM50091326 (CHEMBL3582248) Show SMILES CC(C)c1cc(nn2cc(nc12)C(=O)N1CCN(CC1(C)C)C(=O)OC(C)(C)C)-c1ccc(F)cc1 Show InChI InChI=1S/C27H34FN5O3/c1-17(2)20-14-21(18-8-10-19(28)11-9-18)30-33-15-22(29-23(20)33)24(34)32-13-12-31(16-27(32,6)7)25(35)36-26(3,4)5/h8-11,14-15,17H,12-13,16H2,1-7H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Antagonist activity against PAR2 in human HT29 cells assessed as inhibition of thrombin-induced Ca2+ responses pre-incubated for 30 mins before throm...				ACS Med Chem Lett 6: 487-8 (2015) Article DOI: 10.1021/acsmedchemlett.5b00147 BindingDB Entry DOI: 10.7270/Q27W6DX3
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM50091326 (CHEMBL3582248) Show SMILES CC(C)c1cc(nn2cc(nc12)C(=O)N1CCN(CC1(C)C)C(=O)OC(C)(C)C)-c1ccc(F)cc1 Show InChI InChI=1S/C27H34FN5O3/c1-17(2)20-14-21(18-8-10-19(28)11-9-18)30-33-15-22(29-23(20)33)24(34)32-13-12-31(16-27(32,6)7)25(35)36-26(3,4)5/h8-11,14-15,17H,12-13,16H2,1-7H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Antagonist activity against PAR2 in human HT29 cells assessed as inhibition of UTP-induced Ca2+ responses pre-incubated for 30 mins before UTP stimul...				ACS Med Chem Lett 6: 487-8 (2015) Article DOI: 10.1021/acsmedchemlett.5b00147 BindingDB Entry DOI: 10.7270/Q27W6DX3
					More data for this Ligand-Target Pair