BindingDB PrimarySearch

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proteinase-activated receptor 2' and Ligand = 'BDBM50339247'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM50339247 (6-amino-N-((4S,7S,13S,16S)-13-sec-butyl-4-carbamoy...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels by in vitro physiological response assay				J Med Chem 54: 1308-13 (2011) Article DOI: 10.1021/jm1013049 BindingDB Entry DOI: 10.7270/Q2319W6R
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair